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Invitrogen™ HTR1B Polyclonal Antibody
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Catalog No. 01676664
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100 μg
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Catalog No. Quantity
01-676-664 100 μg
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Catalog No. 01-676-664 Supplier Invitrogen™ Supplier No. PA141069
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Description

Rabbit Polyclonal Antibody

Suggested positive control: human, mouse, or rat brain.

Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase. Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum. In situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HTR1B
Applications Western Blot
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene HTR1B
Gene Accession No. P28222, P28334, P28564
Gene Alias 5-HT>1B> receptor; 5ht1b; 5-HT1B; 5-HT-1B; 5HT1B Receptor; 5-HT1B receptor; 5-HT1B serotonin receptor; 5-HT1DB; 5-HT-1D-beta; 5-hydroxytryptamine (serotonin ) receptor 1B; 5-hydroxytryptamine (serotonin) receptor 1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; 5-hydroxytryptamine receptor 1B; HTR1B; HTR1D2; HTR1DB; S12; serotonin (5-hydroxytryptamine (5HT)) receptor type 1B; serotonin 1D beta receptor; Serotonin receptor 1B
Gene Symbols HTR1B
Host Species Rabbit
Immunogen Mixture of synthetic peptides corresponding to amino acids 8-26 and 263-278 of rat 5-HT1BR.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15551, 25075, 3351
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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