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Sino Biological Human A2aR-Nanodisc Protein (His & Flag Tag, thermostabilizing mutations) 500ug
Supplier: Sino Biological 12307H18H1NA500
A DNA sequence encoding the human AA2AR (P29274) (Met1-Ala316, thermostabilizing mutations) was expressed, with a Flag tag at the N-terminus and a polyhistidine tag at the C-terminus.Nanodisc is a versatile tool for studying membrane proteins. Using styrene-maleic acid (SMA) copolymer, membrane proteins can be extracted directly from prokaryotic and eukaryotic expression systems in the absence of detergents to preserve the protein structure and function better. Compared to membrane scaffold proteins (MSPs) nanodiscs, SMA nanodiscs also have the advantage of preserving proteins' nature by maintaining native lipids surrounded without introducing any heterologous proteins, which allows studies of protein structure and functions in a native-like environment.
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