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Abnova™ Human ABCG2 Full-length ORF (AAH21281.1) Recombinant Protein without tag
Shop All Abnova Corporation ProductsDescription
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq]
Specifications
Specifications
| Accession Number | AAH21281.1 |
| For Use With (Application) | Antibody Production, Compound Screening, Functional Study |
| Formulation | 25mM Tris-HCl of pH8.0 containing 2% glycerol. |
| Gene ID (Entrez) | 9429 |
| Molecular Weight (g/mol) | 72.3kDa |
| Name | ABCG2 (Human) Recombinant Protein |
| Quantity | 2 μg |
| Storage Requirements | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Regulatory Status | RUO |
| Gene Alias | ABC15/ABCP/BCRP/BCRP1/BMDP/CD338/CDw338/EST157481/MGC102821/MRX/MXR/MXR1 |
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