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Invitrogen™ Human ACE2 (aa1-615) Fc Chimera Recombinant Protein

Catalog No. PIRP87692
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100 μg
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Catalog No. Quantity
PIRP87692 200 μg
PIRP87693 1 mg
PIRP87677 100 μg
PIRP87691 50 μg
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Catalog No. PIRP87692 Supplier Invitrogen™ Supplier No. RP87692
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Description

Recombinant Protein

RP-87677 has been tested in indirect ELISA.

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9BYF1
Concentration 1 mg/mL
For Use With (Application) Control, ELISA Standard, Binding Assay
Formulation PBS with no preservative
Gene ID (Entrez) 59272
Molecular Weight (g/mol) 110 kDa
Name Human ACE2 (aa1-615) Fc Chimera
Purification Method Purified
Quantity 200 μg
Source HEK293 cells
Storage Requirements -20°C or -80°C if preferred
Regulatory Status RUO
Gene Alias 2010305L05Rik; ACE 2; Ace2; ACEH; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin I converting enzyme 2; angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; anigotensin I converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; metalloprotease MPROT15; peptidyl-dipeptidase A; Processed angiotensin-converting enzyme 2; renal angiotensin-converting enzyme 2; UNQ868/PRO1885
Common Name ACE2
Gene Symbol ACE2
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag Fc-tag
Sequence Human ACE2 recombinant protein contains amino acids 1 -615 with a human Fc tag
Content And Storage -20°Cor to +80°C if preferred
Expression System HEK293 cells
Form Liquid
Purity or Quality Grade >95% by SDS-PAGE under reducing conditions
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