Gibco™ Human alpha-Defensin 1 Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Supplier:  Gibco™ 3004250UG

Catalog No. 300-42-50UG

Description

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Specifications

• Accession Number: P59665
• Format: Lyophilized
• Gene ID (Entrez): 1667
• Name: Human alpha-Defensin 1
• Quantity: 50 µg
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/µg
• Gene Symbol: DEFA1
• Conjugate: Unlabeled
• Sequence: ACYCRIPACI AGERRYGTCI YQGRLWAFCC

• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 3.4
• Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: alpha-defensin 1; Cryptdin-1; DEF1; Defa1; DEFA1B; DEFA2; Defcr; Defcr1; defensin alpha 1; defensin related cryptdin peptide 1; defensin, alpha 1; defensin, alpha 1, myeloid-related sequence; defensin, alpha 2; defensin-1; defensin-related cryptdin peptide; HNP-1; HNP-2; HP 1-56; HP1; HP-1; HP-2; MRS; myeloid-related sequence; neutrophil defensin 1; Neutrophil defensin 2
• Specific Reactivity: Human
• Recombinant: Yes