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Abnova™ Human ANXA7 (NP_001147, 1 a.a. - 466 a.a. ) Full-length Recombinant Protein with His tag

Used for SDS-PAGE

Manufacturer:  Abnova™ P5846

Catalog No. 89-935-166

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Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq]



Escherichia coli expression system
ANXA7 (Human) Recombinant Protein
>85% by SDS - PAGE
100 ug
Escherichia coli
Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
In 20mM Tris-HCl buffer, pH 8.0 (40% glycerol, 0.15M NaCl, 1mM DTT).
Escherichia coli expression system
3 ug/lane in 15% SDS-PAGE Stained with Coomassie Blue. Due to the protein nature, dimmers and multimers may be observed.
Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
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