Gibco™ Human BD-4 Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Human BD-4 is a 6.0 kDa protein containing 50 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy.

Specifications

• Accession Number: Q8WTQ1
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 140596
• Molecular Weight (g/mol): 6 kDa
• Name: Human BD-4
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: BD-4; Beta-defensin 104; Beta-defensin 4; DEFB104; DEFB104A; DEFB104B; DEFB4; DEFB-4; defensin beta 104 A; Defensin, beta 104; defensin, beta 104 A; defensin, beta 4; hBD-4
• Common Name: DEFB104A
• Gene Symbol: DEFB104A
• Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100.0 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.