Gibco™ Human BD-5 Recombinant Protein, PeproTech®

Catalog No.	Quantity
300-68-1MG	1 mg
30068100UG	100 μg
300-68-20UG	20 μg
30068250UG	250 μg
30068500UG	500 μg
300-68-5UG	5 μg

Catalog No. 300-68-1MG Supplier Gibco™ Supplier No. 300681MG

Description

Recombinant Protein

Recombinant Human BD-5 is a 5.8 kDa protein containing 51 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.

Specifications

• Accession Number: Q8NG35
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 245908, 504180
• Molecular Weight (g/mol): 5.8 kDa
• Name: Human BD-5
• Quantity: 1 mg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Common Name: beta-5 Defensin
• Gene Symbol: DEFB105A, DEFB105B
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: GLDFSQPFPS GEFAVCESCK LGRGKCRKEC LENEKPDGNC RLNFLCCRQR I
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.