R&D Systems™ Human BMP-3b/GDF-10 (NP_004953) VersaClone cDNA

Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

• Also known as: BIP; BMP3B; BMP3b
• GDF-10 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins.
• Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.
• The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer.
• This promotes neural repair after stroke.
• Additionally, GDF10 may act as a tumor suppressor and reduced expression of GDF10 is associated with oral cancer.
• The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
• For reasearch use only. Not for use in humans.

Specifications

• Gene: hGDF10
• Accession Number: NP_004953
• Concentration: 10 μg at 0.2 μg/μL
• Formulation: cDNA is provided in 10 mM Tris-Cl, pH 8.5
• Insert Type: 1450 bp
• Gene ID (Entrez): 2662
• Gene Alias: BIP, BMP-3b, BMP3B, bone morphogenetic protein 3B, Bone-inducing protein, GDF10, GDF-10, growth differentiation factor 10, Growth/differentiation factor 10
• Content And Storage: Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Species: Human
• Quantity: 10 μg