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Gibco™ Human BMP-6 Recombinant Protein, PeproTech®

Catalog No. 1200650UG
Encompass_Preferred
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Quantity:
10 μg
100 μg
2 μg
2 x 500 μg
250 μg
50 μg
500 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Recombinant Protein

120-06-1MG will be provided as 2 x 500 μg (120-06-500UG). Recombinant Human BMP-6 is a 26.2 kDa homodimeric glycoprotein consisting of two 117 amino acid subunits, which correspond to amino acid residues 397 to 513 of the full-length BMP-6 precursor. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

BMP6 is a member of bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, Bmp6 has a proposed role in early development. In addition, the fact that BMP6 is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P22004
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 654
Molecular Weight (g/mol) 26.2 kDa
Name Human BMP-6
Quantity 50 μg
Source HEK293 cells
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias BMP; BMP 6; BMP6; BMP-6; Bone morphogenetic protein; Bone morphogenetic protein 6; D13Wsu115e; vegetal related growth factor (TGFB-related); vegetal-related (TGFB related) cytokine; VG-1-R; VG-1-related protein; Vg1-related sequence; Vgr; Vgr1; VGR-1
Common Name BMP6
Gene Symbol BMP6
Biological Activity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 ug/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence VSSASDYNSS ELKTACRKHE LYVSFQDLGW QDWIIAPKGY AANYCDGECS FPLNAHMNAT NHAIVQTLVH LMNPEYVPKP CCAPTKLNAI SVLYFDDNSN VILKKYRNMV VRACGCH
Content And Storage -20°C
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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