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Gibco™ Human BMP-7 Recombinant Protein, PeproTech®

Catalog No. 12003P100UG
Encompass_Preferred
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Quantity:
10 μg
10 x 100 μg
100 μg
2 μg
5 x 100 μg
50 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Recombinant Protein

120-03P-1MG will be provided as 10 x 100 μg (120-03P-100UG). 120-03P-500UG will be provided as 5 x 100 μg (120-03P-100UG). Recombinant Recombinant Human BMP-7 has a calculated molecular weight of 26.4 kDa; however, due to glycosylation, the BMP-7 homodimer migrates at an apparent molecular weight of approximately 25-35 kDa by SDS-PAGE analysis under non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P18075
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 655
Molecular Weight (g/mol) 26.4 kDa
Name Human BMP-7
Quantity 100 μg
Source CHO cells
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias BMP; BMP7; BMP-7; bone moorphogenic protein-7; Bone morphogenetic protein; bone morphogenetic protein 7; bone morphogenetic protein 7 (osteogenic protein 1); bone morphogenetic protein 7 preproprotein; bone morphogenic protein 7; Eptotermin alfa; OP1; OP-1; Osteogenic protein 1; RP11-560A15.5
Common Name BMP-7
Gene Symbol Bmp7
Biological Activity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.02-0.04 ug/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH
Content And Storage -20°C
Expression System CHO cells
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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