Abnova™ Human BRAF (NM_004333.2, 417 a.a. - 766 a.a.) V600E mutant Partial Protein with GST-His tag expressed in Sf9 cells

Catalog No.	Quantity
89-936-849	100 μg

Catalog No. 89-936-849 Supplier Abnova™ Supplier No. P4833

Description

Used for Func, SDS-PAGE

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq]

Specifications

• Accession Number: NM_004333.2
• Concentration: 0.190 ug/uL
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 673
• Molecular Weight (g/mol): 69.157kDa
• Name: BRAF (V600E) (Human) Recombinant Protein
• Preparation Method: Insect cell (Sf9) expression system
• Purification Method: GST affinity chromatography
• Quality Control Testing: 2 ug/lane SDS-PAGE Stained with Coomassie Blue
• Quantity: 100 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing
• Regulatory Status: RUO
• Gene Alias: B-RAF1/BRAF1/FLJ95109/MGC126806/MGC138284/RAFB1
• Common Name: BRAF
• Gene Symbol: BRAF
• Biological Activity: 197pmol/μg x min
• Species: Baculovirus
• Protein Tag: GST-His
• Expression System: Insect cell (Sf9) expression system
• Form: Liquid