Abnova™ Human C2 Full-length Recombinant Protein with N-terminal hexahistidine tag expressed in in HEK293 cells

Catalog No.	Quantity
89-937-378	100 μg

Catalog No. 89-937-378 Supplier Abnova™ Supplier No. P5886

Description

Used for SDS-PAGE

Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined

Specifications

• Concentration: 0.4 mg/mL
• For Use With (Application): SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 717
• Name: C2 (Human) Recombinant Protein
• Preparation Method: Mammalian cell (HEK293) expression system
• Quality Control Testing: NuPAGE Stained with Coomassie Blue
• Quantity: 100 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: CO2/DKFZp779M0311
• Common Name: C2
• Gene Symbol: C2
• Cross Reactivity: Human ;Human
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His
• Expression System: Mammalian cell (HEK293) expression system
• Form: Liquid