Gibco™ Human CCL15 (MIP-5) Recombinant Protein

Catalog No.	Quantity
PHC1544	25 μg

Catalog No. PHC1544 Supplier Gibco™ Supplier No. PHC1544

Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute MIP-5 in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1.0% BSA. Storage: This lyophilized preparation is stable at room temperature for 1 month. The reconstituted preparation should be apportioned into working aliquots and stored at ≤20C°for up to 3 months with a carrier protein. Avoid repeated freeze/thaw cycles.

This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14).

Specifications

• Accession Number: Q16663
• For Use With (Application): Bioactivity
• Formulation: Protein with no preservative
• Gene ID (Entrez): 6359
• Molecular Weight (g/mol): 10.1 kDa
• Name: Human CCL15 (MIP-5)
• Purification Method: Purified
• Quantity: 25 μg
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <0.1 ng/μg
• Gene Alias: C-C motif chemokine 15; C-C motif chemokine ligand 15; CCL15; CCL15(22-92); CCL15(25-92); CCL15(29-92); chemokine (C-C motif) ligand 15; chemokine CC-2; HCC-2; HCC-2Lkn-1; HMRP-2B; leukotactin 1; Leukotactin-1; LKN1; LKN-1; Macrophage inflammatory protein 5; MIP-1 delta; MIP-1D; MIP5; MIP-5; MIP-5MIP-1d; Mrp-2b; NCC3; NCC-3; NCC-3MIP-1D; NCC3MRP-2B; new CC chemokine 3; SCYA15; SCYA15member 15; SCYL3; small inducible cytokine subfamily A (Cys-Cys), member 15; small-inducible cytokine A15; SY15
• Common Name: MIP-1 delta
• Gene Symbol: CCL15
• Biological Activity: ED50 = 1 - 10 ng/mL; determined by the dose-dependent chemotaxis of human T-lymphocytes.
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Sequence: Human CCL15 recombinant protein contains 92 amino acids
• Content And Storage: -20°C
• Classification: Carrier-Free
• Activity: ED50 = 1 - 10 ng/mL; determined by the dose-dependent chemotaxis of human T-lymphocytes.
• Endotoxin Level: <0.1 ng/μg
• Shipping Condition: Wet Ice
• Expression System: E. coli
• Protein Family: Chemokines & Receptors
• Protein Form: Recombinant, Ligand
• Form: Lyophilized
• Protein Subtype: MIP (Macrophage Inflammatory Protein) Chemokines
• Research Category: Immunology, Inflammation, Signal Transduction, Neurobiology
• Product Line: Gibco
• Purity or Quality Grade: >98% by SDS-PAGE