Gibco™ Human CCL22 (MDC) (67 aa) Recombinant Protein, PeproTech®

Catalog No.	Quantity
300-36-1MG	1 mg
30036100UG	100 μg
300-36-20UG	20 μg
30036250UG	250 μg
30036500UG	500 μg
300-36-5UG	5 μg

Catalog No. 300-36-1MG Supplier Gibco™ Supplier No. 300361MG

Description

Recombinant Protein

Recombinant Human MDC is an 8.0 kDa protein containing 67 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Also, it is a chemotactic for monocytes. dendritic cells and natural killer cells. CCL22 is a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.

Specifications

• Accession Number: O00626
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 6367
• Molecular Weight (g/mol): 8 kDa
• Name: Human CCL22 (MDC) (67 aa)
• Quantity: 1 mg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: A-152E5.1; Abcd1; ABCD-1; Activated B and dendritic cell-derived; AW060611; CC chemokine ABCD-1; CC chemokine STCP-1; C-C motif chemokine 22; C-C motif chemokine ligand 22; Ccl22; chemokine (C-C motif) ligand 22; DC/B-CK; DCBCK; dendritic cell and B cell derived chemokine; macrophage-derived chemokine; MDC; MDC(1-69); MDC(3-69); MDC(5-69); MDC(7-69); MGC108943; MGC34554; RP24-69A20.1; Scya22; small inducible cytokine A22; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED); small inducible cytokine subfamily A (Cys-Cys) member 22; small inducible cytokine subfamily A (Cys-Cys), member 22; small inducible cytokine subfamily A, member 22; small inducible cytokine subfamily A22; small-inducible cytokine A22; STCP-1; stimulated T cell chemotactic protein 1; stimulated T-cell chemotactic protein 1
• Common Name: MDC
• Gene Symbol: CCL22
• Biological Activity: Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: YGANMEDSVC CRDYVRYRLP LRVVKHFYWT SDSCPRPGVV LLTFRDKEIC ADPRVPWVKM ILNKLSQ
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.