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Abnova™ Human CD27 Full-length ORF (NP_001233.1) Recombinant Protein without tag
Shop All Abnova Corporation ProductsDescription
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq]
Specifications
Specifications
| Accession Number | NP_001233.1 |
| For Use With (Application) | Antibody Production, Compound Screening, Functional Study |
| Formulation | Liquid |
| Gene ID (Entrez) | 939 |
| Molecular Weight (g/mol) | 29.2kDa |
| Name | CD27 (Human) Recombinant Protein |
| Quantity | 10 μg |
| Immunogen | MARPHPWWLCVLGTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQRSLCSSDFIRILVIFSGMFLVFTLAGALFLHQRRKYRSNKGESPVEPAEPCRYSCPREEEGSTIPIQEDYRKPEPACSP |
| Storage Requirements | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Regulatory Status | RUO |
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