Invitrogen™ Human CDIP1 Synthetic Peptide

Catalog No.	Quantity
PEP0812	50 μg

Catalog No. PEP0812 Supplier Invitrogen™ Supplier No. PEP0812

Description

Synthetic Peptide

CDIP Synthetic Peptide, PEP-0812, from Invitrogen.

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.

Specifications

• Gene ID (Entrez): 29965
• Species: Human
• Purification Method: purified
• Accession Number: Q9H305
• Common Name: Human CDIP1
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: CDIP1
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS