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  5. Invitrogen™ Human CDNF ELISA Kit 

Invitrogen™ Human CDNF ELISA Kit

Catalog No. EH101RBX10
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EH101RBX10 10 x 96 Tests
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EH101RB 96 Tests
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Catalog No. EH101RBX10 Supplier Invitrogen™ Supplier No. EH101RBX10
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Description

ELISA

Human CDNF quantitates human CDNF in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CDNF.

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number 9330140G23; Arginine-rich protein mutated in early stage tumors-like 1; arginine-rich, mutated in early stage tumors-like 1; ARMETL1; ARMET-like protein 1; Cdnf; cerebral dopamine neurotrophic factor; Conserved dopamine neurotrophic factor
Assay Range 6 to 1,500 pg/mL
Assay Sensitivity 6 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 441549
Gene Symbol Cdnf
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 10 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target CDNF
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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