Abnova™ Human CFB Full-length Recombinant Protein with N-terminal hexahistidine tag expressed in in HEK293EBNA1 cells

Catalog No.	Quantity
89-939-310	100 μg

Catalog No. 89-939-310 Supplier Abnova™ Supplier No. P5887

Description

Used for SDS-PAGE

This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq]

Specifications

• Concentration: 1.6 mg/mL
• For Use With (Application): SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 629
• Name: CFB (Human) Recombinant Protein
• Preparation Method: Mammalian cell (HEK293EBNA1) expression system
• Quality Control Testing: NuPAGE Stained with Coomassie Blue
• Quantity: 100 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: BF/BFD/CFAB/FB/FBI12/GBG/H2-Bf/PBF2
• Common Name: CFB
• Gene Symbol: CFB
• Cross Reactivity: Human ;Human
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His
• Expression System: Mammalian cell (HEK293EBNA1) expression system
• Form: Liquid