Invitrogen™ Human CISD2 Synthetic Peptide

Catalog No.	Quantity
PEP1588	50 μg

Catalog No. PEP1588 Supplier Invitrogen™ Supplier No. PEP1588

Description

Synthetic Peptide

CISD2 Synthetic Peptide, PEP-1588, from Invitrogen.

Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.

Specifications

• Gene ID (Entrez): 493856
• Species: Human
• Purification Method: purified
• Accession Number: Q8N5K1
• Common Name: Human CISD2
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: CISD2
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS