R&D Systems™ Human Coagulation Factor X (NP_000495) VersaClone cDNA

Catalog No.	Quantity
RDC2720	10 μg

Catalog No. RDC2720 Supplier R&D Systems™ Supplier No. RDC2720

Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

• Also known as: FX; FXA
• Factor X is a vitamin K-dependent coagulation factor X of the blood coagulation cascade.
• This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR.
• The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).
• The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.
• Mutations of Factor X result in factor X deficiency, a hemorrhagic condition of variable severity.
• The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
• For reasearch use only. Not for use in humans.

Specifications

• Gene: hF10
• Accession Number: NP_000495
• Concentration: 10 μg at 0.2 μg/μL
• Formulation: cDNA is provided in 10 mM Tris-Cl, pH 8.5
• Insert Type: 1480 bp
• Gene ID (Entrez): 2159
• Content And Storage: Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Species: Human
• Quantity: 10 μg