Gibco™ Human CXCL12 (SDF-1b) Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Human SDF-1beta is an 8.5 kDa protein containing 72 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: P48061
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 6387
• Molecular Weight (g/mol): 8.5 kDa
• Name: Human CXCL12 (SDF-1 b)
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C x C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; CXCL12; Intercrine reduced in hepatomas; IRH; PBSF; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; Sdf1; SDF-1; sdf-1 beta; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); Stromal cell-derived factor 1; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1
• Common Name: CXCL12 beta
• Gene Symbol: Cxcl12
• Biological Activity: Determined by its ability to chemoattract activated human T-lymphocytes using a concentration range of 10-50 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.