Gibco™ Human CXCL4 (PF4) Recombinant Protein, PeproTech®

Catalog No.	Quantity
300-16-1MG	1 mg
30016100UG	100 μg
300-16-20UG	20 μg
30016250UG	250 μg
30016500UG	500 μg
300-16-50UG	50 μg
300-16-5UG	5 μg

Catalog No. 300-16-1MG Supplier Gibco™ Supplier No. 300161MG

Description

Recombinant Protein

Recombinant Human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990).

Specifications

• Accession Number: P02776
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 5196
• Molecular Weight (g/mol): 7.8 kDa
• Name: Human CXCL4 (PF4)
• Quantity: 1 mg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: chemokine (C-X-C motif) ligand 4; C-X-C motif chemokine 4; Cxcl4; Endothelial cell growth inhibitor; Iroplact; oncostatin-A; PF4; PF-4; Pf4a; Platelet factor 4; Platelet factor 4, short form; RATPF4A; Scyb4
• Common Name: PF4
• Gene Symbol: Pf4
• Biological Activity: Determined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.