Invitrogen™ Human DDX60 Synthetic Peptide

Catalog No.	Quantity
PEP1484	50 μg

Catalog No. PEP1484 Supplier Invitrogen™ Supplier No. PEP1484

Description

Synthetic Peptide

DDX60 Synthetic Peptide, PEP-1484, from Invitrogen.

DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling.

Specifications

• Gene ID (Entrez): 55601
• Species: Human
• Purification Method: purified
• Accession Number: Q8IY21
• Common Name: Human DDX60
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: DDX60
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS