Invitrogen™ Human DIS3 Synthetic Peptide

Catalog No.	Quantity
PEP1592	50 μg

Catalog No. PEP1592 Supplier Invitrogen™ Supplier No. PEP1592

Description

Synthetic Peptide

DIS3 Synthetic Peptide, PEP-1592, from Invitrogen.

The exosome is involved in a multitude of cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.

Specifications

• Gene ID (Entrez): 22894
• Species: Human
• Purification Method: purified
• Accession Number: Q9Y2L1
• Common Name: Human DIS3
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: DIS3
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS