Abnova™ Human DYRK3 (NP_003573.2, 1 a.a. - 588 a.a.) Full-length Recombinant Protein with GST-tag expressed in baculovirus infected Sf21 cells

Catalog No.	Quantity
89-942-642	5 μg

Catalog No. 89-942-642 Supplier Abnova™ Supplier No. P5542

Description

Used for Func, SDS-PAGE

This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Specifications

• Accession Number: NP_003573.2
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 8444
• Molecular Weight (g/mol): 93kDa
• Name: DYRK3 (Human) Recombinant Protein
• Preparation Method: Baculovirus infected insect cell (Sf21) expression system
• Purification Method: Glutathione sepharose chromatography
• Quality Control Testing: Loading 1 ug protein in SDS-PAGE
• Quantity: 5 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: DYRK5/RED/REDK/hYAK3-2
• Common Name: DYRK3
• Gene Symbol: DYRK3
• Biological Activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: DYRKtide-F. ATP: 100 uM.
• Species: Baculovirus
• Recombinant: Recombinant
• Protein Tag: GST
• Expression System: Baculovirus infected insect cell (Sf21) expression system
• Form: Liquid
• Purity or Quality Grade: 93% by SDS-PAGE/CBB staining