Gibco™ Human Eotaxin-3 (CCL26) Recombinant Protein, PeproTech®

Catalog No.	Quantity
30048500UG	500 μg
30048100UG	100 μg
300-48-1MG	1 mg
300-48-20UG	20 μg
30048250UG	250 μg
300-48-5UG	5 μg

Catalog No. 30048500UG Supplier Gibco™ Supplier No. 30048500UG

Description

Recombinant Protein

Recombinant Human Eotaxin-3 is an 8.4 kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.

Specifications

• Accession Number: Q9Y258
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 10344
• Molecular Weight (g/mol): 8.4 kDa
• Name: Human Eotaxin-3 (CCL26)
• Quantity: 500 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: CC chemokine IMAC; C-C motif chemokine 26; C-C motif chemokine ligand 26; Ccl26; Ccl26l; chemokine (C-C motif) ligand 26; chemokine N1; Eotaxin3; eotaxin-3; IMAC; Macrophage inflammatory protein 4-alpha; MGC126714; MIP-4 A; MIP-4 alpha; MIP-4-alpha; PRO242; SCYA26; SCYA26MIP-4-alpha; small inducible cytokine A26; small inducible cytokine subfamily A (Cys-Cys), member 26; small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; UNQ216; UNQ216/PRO242
• Common Name: Eotaxin 3
• Gene Symbol: CCL26
• Biological Activity: Determined by its ability to chemoattract human CCR3/HEK293 cells. The maximum activity was achieved (at 2 ug/ml)
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.