Invitrogen™ Human Fc gamma RIIB (CD32b) His-tag Recombinant Protein

Catalog No.	Quantity
PIRP87989	1 mg
PIRP87988	100 μg

Catalog No. PIRP87989 Supplier Invitrogen™ Supplier No. RP87989

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (599 μL) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV.

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.

Specifications

• Accession Number: P31994
• For Use With (Application): Control, ELISA Standard, Binding Assay
• Format: Lyophilized
• Formulation: PBS with 15% trehalose and no preservative; pH 7.4
• Gene ID (Entrez): 2213
• Molecular Weight (g/mol): 25-30 kDa
• Name: Human Fc gamma RIIB (CD32b) His-tag
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 1 mg
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Endotoxin Concentration: <1.0 EU/μg
• Gene Alias: AI528646; CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CD32B; CDw32; F630109E10Rik; Fc fragment of IgG receptor IIb; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); fc gamma receptor IIB; Fc gamma RIIb; Fc receptor, IgG, low affinity IIb; Fc[g]RII; FCG2; FC-gamma RII; fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma-RII; fc-gamma-RIIa; FcgammaRIIB; fc-gamma-RIIb; FcgammaRIIB2; FcGR; Fcgr2; Fcgr2a; FCGR2A1; FCGR2B; FcgRII; Fcr-2; Fcr-3; fcRII; fcRII-a; fcRII-b; FGFR2B; IGFR2; IgG Fc receptor II beta; igG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II; low affinity immunoglobulin gamma Fc region receptor II-b; Ly-17; LyM-1; Ly-m20; Lymphocyte antigen 17
• Common Name: CD32b (FCGR2B)
• Gene Symbol: FCGR2B
• Biological Activity: Measured by its ability to bind biotinylated human IgG2 in functional ELISA.
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Human CD32b, amino acids Ala46-Pro217 (Accession # NP_001002274.1) with a C-terminal His-tag
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Activity: Recombinant Human CD32b / FCGR2B Protein (His Tag) (Cat: 10259-H08H) was captured on a CM5 chip via Anti-His antibody, and its binding to Anti-CD20 (Research Grade Rituximab Biosimilar) was evaluated in an SPR assay (Biacore T200).
• Expression System: HEK293 cells
• Form: Lyophilized
• Purity or Quality Grade: ≥95% as determined by SDS-PAGE. ≥95% as determined by SEC-HPLC.