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Gibco™ Human FGF-18, Animal-Free Recombinant Protein, PeproTech®

Catalog No. AF10028100
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100 μg
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Catalog No. Quantity
AF10028100 100 μg
AF100281MG 1 mg
AF1002825UG 25 μg
AF10028500 500 μg
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Catalog No. AF10028100 Supplier Gibco™ Supplier No. AF10028100UG
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Description

Recombinant Protein

Recombinant Human FGF-18 derived from E.coli is a 20.1 kDa protein consisting of 173 amino acid residues, resulting from C-terminal truncation of the full length protein. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O76093
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 8817
Molecular Weight (g/mol) 20.1 kDa
Name Human FGF-18, Animal-Free
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <0.1 EU/ μg
Gene Alias D130055P09Rik; FGF; FGF18; FGF-18; Fibroblast growth factor; Fibroblast growth factor 18; UNQ420/PRO856; zFGF5
Common Name FGF18
Gene Symbol Fgf18
Biological Activity Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 10^5 units/mg
Conjugate Unconjugated
Recombinant Recombinant
Sequence AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSR
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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