Gibco™ Human FGF-acidic (FGF-1) Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Human FGF-acidic is a 16.8 kDa protein consisting of 141 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.

Specifications

• Accession Number: P05230
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 2246
• Molecular Weight (g/mol): 16.8 kDa
• Name: Human FGF-acidic (FGF-1)
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: acidic eye-derived fibroblast growth factor; acidic eye-derived growth factor II; Acidic fibroblast growth factor; aFGF; beta-endothelial cell growth factor; Dffrx; ECGF; ECGFA; ECGFB; ECGF-beta; EDGF; EDGF II; Endothelial cell growth factor; Endothelial cell growth factor alpha; Endothelial cell growth factor beta; endothelial cell growth factor beta and alpha chains; endothelial cell growth factor, alpha; endothelial cell growth factor, beta; endothelial growth factor; Fam; FGF; FGF1; Fgf-1; FGF1 protein; Fgfa; FGF-alpha; Fibroblast growth factor; Fibroblast growth factor 1; fibroblast growth factor 1 (acidic); Fibroblast growth factor 1 (heparin binding); fibroblast growth factor, acidic; GLIO703; HBGF1; HBGF-1; heparin-binding growth factor; Heparin-binding growth factor 1; H-FGF-a; M-FGF-a; Prostatropin; unnamed protein product
• Common Name: FGF1
• Gene Symbol: FGF1
• Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.5 ng/ml in the presence of 10 ug/ml heparin, corresponding to a specific activity of ≥ 2 x 10^6 units/mg
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.