Gibco™ Human gAcrp30/Adipolean Recombinant Protein, PeproTech®

Description

Recombinant Protein

450-21-1MG will be provided as 2 x 500 μg (450-21-500UG). Recombinant Human gAcrp30/Adipolean is a 16.6 kDa protein consisting of 145 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

gAcrp30 is a naturally occurring globular protein obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, gAcrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs). The signaling receptors for adiponectin and gAcrp30 have recently been identified and named AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver.

Specifications

• Accession Number: Q15848
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 9370
• Molecular Weight (g/mol): 16.6 kDa
• Name: Human gAcrp30/Adipolean
• Quantity: 250 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <2 EU/ μg
• Gene Alias: gAcrp30
• Common Name: Adipolean
• Gene Symbol: ADIPOQ
• Biological Activity: Determined by its ability to inhibit the proliferation of murine M1 cells. The expected ED50 for this effect is 1.0-3.0 ug/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MKGEPGEGAY VYRSAFSVGL ETYVTIPNMP IRFTKIFYNQ QNHYDGSTGK FHCNIPGLYY FAYHITVYMK DVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEG ERNGLYADND NDSTFTGFLL YHDTN
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.