Human GITR/TNFRSF18 Antibody, R&D Systems™

Mouse Monoclonal Antibody has been used in 9 publications

Supplier:  R&D Systems MAB689SP

Catalog No. MAB689SP

Description

GITR/TNFRSF18 Monoclonal specifically detects GITR/TNFRSF18 in Human samples. It is validated for Western Blot, Flow Cytometry, Blockade of Receptor-ligand Interaction, CyTOF-ready, ELISA Capture (Matched Antibody Pair).

Specifications

• Antigen: GITR/TNFRSF18
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
• Gene Alias: Activation-inducible TNFR family receptor, AITR, AITRTNF receptor superfamily activation-inducible protein, CD357, CD357 antigen, GITR-D, GITRtumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, TNFRSF18, tumor necrosis factor receptor superfamily, member 18
• Host Species: Mouse
• Purification Method: Protein A or G purified from hybridoma culture supernatant
• Regulatory Status: RUO
• Gene ID (Entrez): 8784
• Reconstitution: Reconstitute at 0.5 mg/mL in sterile PBS.
• Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Isotype: IgG1

• Applications: Western Blot, Flow Cytometry, Blockade of Receptor-ligand Interaction, CyTOF, ELISA
• Clone: 110416
• Dilution: Western Blot 1 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, Blockade of Receptor-ligand Interaction 1-2 ug/mL, CyTOF-ready, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
• Gene Accession No.: Q9Y5U5
• Gene Symbols: TNFRSF18
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human GITR/TNFRSF18 Gln26-Glu161 (Thr43Ala) Accession # Q9Y5U5
• Quantity: 25 μg
• Primary or Secondary: Primary
• Test Specificity: Detects human GITR in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) 4-1BB, recombinant mouse (rm) 4-1BB, rhCD27, rmCD27, rhCD30, rmCD30, rhCD40, rmCD40, rhDR3, rhDR6, rhEDAR, rmEDAR, rhFas, rmFAS, rmGITR, rhHVEM, rhLymphotoxin R beta , rmLymphotoxin R beta , rhNGF R, rhOPG, rmOPG, rhRANK, rmRANK, rhTAJ, rhTNF RI, rmTNF RI, rhTNF RII, or rmTNF RII.
• Target Species: Human
• Form: Purified