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Invitrogen™ eBioscience™ Human GM-CSF Platinum ELISA Kit Non-distribution product as customer accommodation.

For the quantitative detection of human GM-CSF.

Manufacturer:  Invitrogen™ BMS283TEN

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Catalog No. 50-182-33


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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human GM-CSF
HRP-Conjugate anti-human GM-CSF monoclonal antibody
Human GM-CSF Standard lyophilized, 1ng/mL upon reconstitution
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Adhesive Films

Description

Description

GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombinant GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).
Specifications

Specifications

P04141
HRP
1437
Adhesive Plate Covers
10 x 96 tests
2.9 pg/mL
50μL
Human
1 hr 20 min
Human
Molgramostin, Sargramostim
6%
7.8-500 pg/mL
ELISA
Colorimetric Microplate Reader
ELISA
RUO
Amniotic Fluid, Plasma, Serum, Supernatants
Amniotic Fluid (50μL), Plasma (50μL), Serum (50μL), Supernatants (50μL)
2-8°C
3 hr 10 min
CSF2
4.4%
HRP
Documents
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