Invitrogen eBioscience Human GM-CSF Platinum ELISA Kit
For the quantitative detection of human GM-CSF.
Manufacturer: Invitrogen BMS283TEN
DescriptionGM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombinant GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).
|Adhesive Plate Covers|
|10 x 96 tests|
|1 hr 20 min|
|Colorimetric Microplate Reader|
|Amniotic Fluid, Plasma, Serum, Supernatants|
|Amniotic Fluid (50μL), Plasma (50μL), Serum (50μL), Supernatants (50μL)|
|3 hr 10 min|
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For Research Use Only