Abnova™ Human GP1BA (NP_000164, 17 a.a - 306 a.a) Partial Protein (single sulfated form) with C-terminal hexahistidine tag expressed in HEK293EBNA1 cells

Catalog No.	Quantity
89-946-309	45 μg

Catalog No. 89-946-309 Supplier Abnova™ Supplier No. P5899

Description

Used for SDS-PAGE

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq]

Specifications

• Accession Number: NP_000164
• For Use With (Application): SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 2811
• Molecular Weight (g/mol): 33.5kDa
• Name: GP1BA N37O/N175O (Human) Recombinant Protein
• Preparation Method: Mammalian cell (HEK293EBNA1) expression system
• Quality Control Testing: NuPAGE Stained with Coomassie Blue
• Quantity: 45 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: BSS/CD42B/CD42b-alpha/GP1B/MGC34595
• Common Name: GP1BA
• Gene Symbol: GP1BA
• Cross Reactivity: Human ;Human
• Species: Human
• Protein Tag: His
• Expression System: Mammalian cell (HEK293EBNA1) expression system
• Form: Liquid