Gibco™ Human HCC-1 (CCL14) (72 aa) Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Human HCC-1 is an 8.4 kDa protein consisting of 72 amino acids, including the four highly conserved residues present in CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

This gene, CCL14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. This gene expresses both monocistronic and bicistronic transcripts. Bicistronic transcripts include the upstream cytokine gene CCL15. In addition, CCL14 undergoes alternative splicing in the bicistronic transcripts; it is unknown if its monocistronic transcript is also subject to alternative splicing.

Specifications

• Accession Number: Q16627
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 6358
• Molecular Weight (g/mol): 8.4 kDa
• Name: Human HCC-1 (CCL14) (72 aa)
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: C-C motif chemokine 14; C-C motif chemokine ligand 14; CC-1; CC-3; CCL14; chemokine (C-C motif) ligand 14; chemokine CC-1/CC-3; chemokine CC-3; CKB1; H HCC-1(1-74); HCC-1; HCC-1(1-74); HCC-1(3-74); HCC-1(4-74); HCC-1(9-74); HCC-1/HCC-3; HCC-3; hemofiltrate CC chemokine 1; MCIF; NCC2; NCC-2; new CC chemokine 2; SCYA14; SCYL2; small inducible cytokine subfamily A (Cys-Cys), member 14; small-inducible cytokine A14; SY14
• Common Name: CCL14
• Gene Symbol: CCL14
• Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-20.0 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.