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Gibco™ Human IGF-BP6 Recombinant Protein, PeproTech®

Catalog No. 35007B500
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Quantity:
100 μg
2 x 250 μg
20 μg
250 μg
4 x 250 μg
5 μg
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Catalog No. Quantity
35-007-B500 2 x 250 μg
35007B100UG 100 μg
35007B20UG 20 μg
35-007-B01M 4 x 250 μg
35007B250UG 250 μg
350-07B-5UG 5 μg
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Catalog No. 35-007-B500 Supplier Gibco™ Supplier No. 35007B500
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Description

Recombinant Protein

350-07B-1MG will be provided as 4 x 250 μg (350-07B-250UG). 350-07B-500UG will be provided as 2 x 250 μg (350-07B-250UG). RecombinantRecombinant Human IGF-BP6 migrates at an apparent molecular weight of approximately 23.0-30.0 kDa by SDS-PAGE analysis under non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6, which specifically inhibits IGF-II actions, is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P24592
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 3489
Molecular Weight (g/mol) 22.3 kDa
Name Human IGF-BP6
Quantity 2 x 250 μg
Source Insect cells
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias IBP6; IBP-6; IGF binding protein 6; IGF-binding protein 6; IGFBP; IGFBP6; IGF-BP6; Igfbp-6; Insulin like growth factor binding protein; insulin like growth factor binding protein 6; insulin-like growth factor binding protein 6; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 6 PRECURSOR (IGFBP-6) (IBP-6) (IGF-BINDING PROTEIN 6); insulin-like growth factor-binding protein 6; RBP6A
Common Name IGFBP6
Gene Symbol IGFBP6
Biological Activity Determined by its ability to inhibit IGF-II induced proliferation of human MCF-7 cells. The expected ED50 for this effect is 0.1 -0.4 ug/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence RCPGCGQGVQ AGCPGGCVEE EDGGSPAEGC AEAEGCLRRE GQECGVYTPN CAPGLQCHPP KDDEAPLRAL LLGRGRCLPA RAPAVAEENP KESKPQAGTA RPQDVNRRDQ QRNPGTSTTP SQPNSAGVQD TEMGPCRRHL DSVLQQLQTE VYRGAQTLYV PNCDHRGFYR KRQCRSSQGQ RRGPCWCVDR MGKSLPGSPD GNGSSSCPTG SSG
Content And Storage -20°C
Expression System Insect cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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