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Abnova™ Human IGFBP3 (P17936, 264 amino acids) Partial Recombinant Protein

Catalog No. 89948487 Shop All Abnova Corporation Products
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25 μg
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Catalog No. Quantity
89-948-487 25 μg
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Catalog No. 89-948-487 Supplier Abnova™ Supplier No. P4128

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Used for Func, SDS-PAGE

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Specifications

Accession Number P17936
For Use With (Application) Functional Study, SDS-PAGE
Formulation Lyophilized
Gene ID (Entrez) 3486
Molecular Weight (g/mol) 28.8kDa
Name IGFBP3 (Human) Recombinant Protein
Preparation Method Escherichia coli expression system
Quantity 25 μg
Storage Requirements Store at -20°C on dry atmosphere. After reconstitution with sterilized water, store at -20°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Endotoxin Concentration <0.1ng/μg
Gene Alias BP-53/IBP3
Common Name IGFBP3
Gene Symbol IGFBP3
Biological Activity The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is < 0.2 mg/mL, in the presence of 15ng/mL of human IGF-II.
Species E. coli
Recombinant Recombinant
Protein Tag None
Expression System Escherichia coli expression system
Form Lyophilized
Purity or Quality Grade ≥98% by SDS-PAGE and HPLC
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