Gibco™ Human IL-17E (IL-25) Recombinant Protein, PeproTech®

Description

Recombinant Protein

200-24-1MG will be provided as 2 x 500 μg (200-24-500UG). Recombinant Human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 146 amino acid polypeptide chains. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis. IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.

Specifications

• Accession Number: Q9H293
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 64806
• Molecular Weight (g/mol): 33.8 kDa
• Name: Human IL-17 E (IL-25)
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: D17Wsu104e; il 17 e; Il17e; IL-17 E; Il25; IL-25; ILN; Interleukin; interleukin 17 E; interleukin 25; interleukin-17 E; Interleukin-25; Ly6elg; Mydgf; myeloid derived growth factor; myeloid-derived growth factor; RGD1561632; UNQ3120/PRO10272; UPF0556 protein C19orf10 homolog
• Common Name: IL-25
• Gene Symbol: IL25
• Biological Activity: Determined by its ability to induce IL-8 in. human PBMCs using a concentration range of 10-100 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MYSHWPSCCP SKGQDTSEEL LRWSTVPVPP LEPARPNRHP ESCRASEDGP LNSRAISPWR YELDRDLNRL PQDLYHARCL CPHCVSLQTG SHMDPRGNSE LLYHNQTVFY RRPCHGEKGT HKGYCLERRL YRVSLACVCV RPRVMG
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.