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Gibco™ Human IL-37 (IL-1F7), Animal-Free Recombinant Protein, PeproTech®

Catalog No. AF20039500
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AF20039500 500 μg
AF20039100 100 μg
AF200391MG 1 mg
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Catalog No. AF20039500 Supplier Gibco™ Supplier No. AF20039500UG
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Description

Recombinant Protein

Recombinant Human IL-37 is a 19.4 kDa protein consisting of 174 amino acids, corresponding to the mature activated form of IL-37. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9NZH6
For Use With (Application) ELISA, Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 27178
Molecular Weight (g/mol) 19.4 kDa
Name Human IL-37 (IL-1F7), Animal-Free
Quantity 500 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <0.1 EU/ μg
Gene Alias FIL1; FIL1 zeta; FIL1(ZETA); FIL1Z; IL-1 zeta; IL1F7; IL-1F7; IL1F7 (canonical product IL-1F7b); IL-1F7b (IL-1H4, IL-1 H, IL-1 RP1); IL-1 H; IL1H4; IL-1H4; IL1RP1; IL-1 RP1; IL-1 X; IL-1 x protein; IL37; IL-37; ILN; Interleukin; interleukin 1 family member 7; interleukin 1, zeta; interleukin 37; Interleukin-1 family member 7; Interleukin-1 homolog 4; interleukin-1 superfamily z; Interleukin-1 zeta; Interleukin-1-related protein; interleukin-23; Interleukin37; Interleukin-37
Common Name IL-37
Gene Symbol IL37
Biological Activity Measured by its ability to bind Interleukin-18 Binding Protein isoform a (IL-18 BPa) in functional ELISA.
Conjugate Unconjugated
Recombinant Recombinant
Sequence MVHTSPKVKN LNPKKFSIHD QDHKVLVLDS GNLIAVPDKN YIRPEIFFAL ASSLSSASAE KGSPILLGVS KGEFCLYCDK DKGQSHPSLQ LKKEKLMKLA AQKESARRPF IFYRAQVGSW NMLESAAHPG WFICTSCNCN EPVGVTDKFE NRKHIEFSFQ PVCKAEMSPS EVSD
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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