Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Abnova™ Human IL12A (P29459, 503 amino acids) Partial Recombinant Protein expressed in CHO cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P3997

Catalog No. 89-948-620

Add to cart



This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq]



Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Mammalian cell (CHO) expression system
10 ug
Mammalian cell (CHO) expression system
IL12A (Human) Recombinant Protein
≥98% by SDS-PAGE and HPLC
Store at -20°C on dry atmosphere. After reconstitution with PBS, store at 4°C for 1 week or -20°C for longer. Aliquot to avoid repeated freezing and thawing.
The ED50 was determined by the induction of IFN-g production from murine splenocytes co-stimulated with IL-12 is < 0.1ng/mL, corresponding to a specific activity of > 1 x 107 units/mg.
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit