Abnova™ Human IL1RN (P18510, 153 amino acids) Partial Recombinant Protein

Catalog No.	Quantity
89-948-781	20 μg

Catalog No. 89-948-781 Supplier Abnova™ Supplier No. P4050

Description

Used for Func, SDS-PAGE

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

• Accession Number: P18510
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: Lyophilized
• Gene ID (Entrez): 3557
• Molecular Weight (g/mol): 17kDa
• Name: IL1RN (Human) Recombinant Protein
• Preparation Method: Escherichia coli expression system
• Quantity: 20 μg
• Storage Requirements: Store at -20°C on dry atmosphere. After reconstitution with sterilized water, store at -20°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: ICIL-1RA/IL-1ra3/IL1F3/IL1RA/IRAP/MGC10430
• Common Name: IL1RN
• Gene Symbol: IL1RN
• Biological Activity: The ED50 as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells was found to be 0.5ng/mL.
• Species: E. coli
• Recombinant: Recombinant
• Protein Tag: None
• Expression System: Escherichia coli expression system
• Form: Lyophilized
• Purity or Quality Grade: ≥98% by SDS-PAGE and HPLC