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Abnova™ Human IL1RN (P18510, 153 amino acids) Partial Recombinant Protein

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P4050

Catalog No. 89-948-781


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Description

Description

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

Specifications

P18510
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Lyophilized
17kDa
Escherichia coli expression system
20 ug
RUO
IL1RN
The ED50 as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells was found to be 0.5ng/mL.
Yes
Escherichia coli expression system
Lyophilized
3557
IL1RN (Human) Recombinant Protein
≥98% by SDS-PAGE and HPLC
Store at -20°C on dry atmosphere. After reconstitution with sterilized water, store at -20°C. Aliquot to avoid repeated freezing and thawing.
ICIL-1RA|IL-1ra3|IL1F3|IL1RA|IRAP|MGC10430
IL1RN
Escherichia coli
None
SDS
Documents
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