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Abnova™ Human IL4 (P05112, His 25 - Ser 153) Partial Recombinant Protein

Catalog No. 89948910 Shop All Abnova Corporation Products
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10 μg
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Catalog No. Quantity
89-948-910 10 μg
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Catalog No. 89-948-910 Supplier Abnova™ Supplier No. P3639

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Used for Func, SDS-PAGE

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

Accession Number P05112
For Use With (Application) Functional Study, SDS-PAGE
Formulation Lyophilized
Gene ID (Entrez) 3565
Molecular Weight (g/mol) 15kDa
Name IL4 (Human) Recombinant Protein
Preparation Method Escherichia coli expression system
Purification Method Ion exchange column and HPLC reverse phase column
Quantity 10 μg
Storage Requirements Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Endotoxin Concentration <0.1ng/μg (1 EU/μg)
Gene Alias BCGF-1/BCGF1/BSF1/IL-4/MGC79402
Common Name IL4
Gene Symbol IL4
Biological Activity The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤0.1ng/mL, corresponding to a specific activity of >1 x 107 units/mg.
Species E. coli
Recombinant Recombinant
Protein Tag None
Expression System Escherichia coli expression system
Form Lyophilized
Purity or Quality Grade >90% by SDS-PAGE and HPLC
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