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Abnova™ Human IL4 (P05112, His 25 - Ser 153) Partial Recombinant Protein

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P3639

Catalog No. 89-948-910

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

Specifications

P05112
Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
Lyophilized
15kDa
Escherichia coli expression system
>90% by SDS-PAGE and HPLC
Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months. Aliquot to avoid repeated freezing and thawing.
<0.1ng/μg (1 EU/μg)
IL4
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤0.1ng/mL, corresponding to a specific activity of >1 x 107 units/mg.
Yes
Escherichia coli expression system
Lyophilized
3565
IL4 (Human) Recombinant Protein
Ion exchange column and HPLC reverse phase column
10 ug
RUO
BCGF-1|BCGF1|BSF1|IL-4|MGC79402
IL4
Escherichia coli
None
Documents
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