Abnova™ Human IL4R (P24394, Met 26 - His 232) Partial Recombinant Protein expressed in HEK293 cells

Catalog No.	Quantity
89-948-920	10 μg

Catalog No. 89-948-920 Supplier Abnova™ Supplier No. P3682

Description

Used for SDS-PAGE

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq]

Specifications

• Accession Number: P24394
• For Use With (Application): SDS-PAGE
• Formulation: Lyophilized
• Gene ID (Entrez): 3566
• Molecular Weight (g/mol): 45kDa
• Name: IL4R (Human) Recombinant Protein
• Preparation Method: Mammalian cell (HEK293) expression system
• Purification Method: Ion exchange column and HPLC reverse phase column
• Quantity: 10 μg
• Storage Requirements: Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 12 months. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Endotoxin Concentration: <0.1ng/μg (1 EU/μg)
• Gene Alias: CD124/IL4RA
• Common Name: IL4R
• Gene Symbol: IL4R
• Species: Human
• Recombinant: Recombinant
• Protein Tag: None
• Expression System: Mammalian cell (HEK293) expression system
• Form: Lyophilized
• Purity or Quality Grade: >90% by SDS-PAGE and HPLC