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ACROBiosystems Recombinant Protein;Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein;HEK293;100UG;IT1,Integrin alpha V beta 1,ITGAV&ITGB1,Integrin,ITGAV,ITGA,ITGB1,ITGB,ITGAVB1
Supplier: ACROBiosystems IT1H52E1100UG
Recombinant Protein;Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein;100UG;Human ITGAV & ITGB1 Heterodimer Protein (IT1-H52E1) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) & Gln 21 - Asp 728 (ITGB1) (Accession # NP_002201 (ITGAV)& P05556 (ITGB1)).;Human ITGAV & ITGB1 Heterodimer Protein, produced by co-expression of ITGAV and ITGB1, has a calculated MW of 113 kDa (ITGAV) and 83.7 kDa (ITGB1). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The predicted N-terminus is Phe 31 (ITGAV) & Gln 21 (ITGB1). The reducing (R) protein migrates as 145 kDa (ITGAV) and 116 kDa (ITGB1) respectively due to glycosylation.;Immobilized Fibronectin at 10 μg/mL (100 μL/well) can bind Human ITGAV & ITGB1 Heterodimer Protein (Cat. No. IT1-H52E1) with a linear range of 0.156-1.25 μg/mL (QC tested).
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