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Invitrogen™ Human KCNMA1 (aa 887-902) Synthetic Peptide

Catalog No. PEP122
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Quantity:
50 μg

Synthetic Peptide

Human Maxi K+ alpha (residues 887-902) Synthetic Peptide, PEP-122, from Invitrogen.

Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 3778
Species Human
Purification Method purified
Accession Number Q12791
Common Name Human KCNMA1 (aa 887-902)
Concentration 0.5 mg/mL
Content And Storage -20°C. Avoid freeze-thaw cycles.
Description Synthetic Peptide
Format Lyophilized
Formulation peptide with no preservative
For Use With (Application) Control
Gene Symbol KCNMA1
Lyophilized Lyophilized
Preservative No preservative
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Sequence Derived from Amino Acids 887-902 of Human Maxi K+ a Protein
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WARNING: Cancer - www.P65Warnings.ca.gov
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