Abnova™ Human KDR (NM_002253, 789 a.a. - end) Partial Recombinant Protein with GST-tag expressed in Sf9 cells

Catalog No.	Quantity
89-949-617	5 μg

Catalog No. 89-949-617 Supplier Abnova™ Supplier No. P3871

Description

Used for Func, SDS-PAGE

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq]

Specifications

• Accession Number: NM_002253
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: In 50mM Tris-HCl, 150mM NaCl, pH 7.5 (0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol)
• Gene ID (Entrez): 3791
• Molecular Weight (g/mol): 110kDa
• Name: KDR (Human) Recombinant Protein
• Preparation Method: Insect cell (Sf9) expression system
• Quality Control Testing: SDS-PAGE Stained with Coomassie Blue
• Quantity: 5 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: CD309/FLK1/VEGFR/VEGFR2
• Common Name: KDR
• Gene Symbol: KDR
• Biological Activity: The specific activity was determined to be 58nmol /min/mg as per Activity Assay Protocol.
• Species: Baculovirus
• Recombinant: Recombinant
• Protein Tag: GST
• Expression System: Insect cell (Sf9) expression system
• Purity or Quality Grade: >70% by densitometry