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Abnova™ Human LIFR (P42702, Gln 45 - Ser 833) Partial Recombinant Protein expressed in HEK293 cells

Catalog No. 89950661 Shop All Abnova Corporation Products
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89-950-661 20 μg
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Catalog No. 89-950-661 Supplier Abnova™ Supplier No. P3681
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Used for SDS-PAGE

This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq]

Specifications

Accession Number P42702
For Use With (Application) SDS-PAGE
Formulation Lyophilized
Gene ID (Entrez) 3977
Molecular Weight (g/mol) 125-135kDa
Name LIFR (Human) Recombinant Protein
Preparation Method Mammalian cell (HEK293) expression system
Purification Method Ion exchange column and HPLC reverse phase column
Quantity 20 μg
Storage Requirements Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at 4°C for one month. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Endotoxin Concentration <0.1ng/μg (1 EU/μg)
Gene Alias CD118/FLJ98106/FLJ99923/LIF-R/SJS2/STWS/SWS
Common Name LIFR
Gene Symbol LIFR
Species Human
Recombinant Recombinant
Protein Tag None
Expression System Mammalian cell (HEK293) expression system
Form Lyophilized
Purity or Quality Grade >90% by SDS-PAGE and HPLC
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