Learn More
Abnova™ Human LIFR (P42702, Gln 45 - Ser 833) Partial Recombinant Protein expressed in HEK293 cells
Shop All Abnova Corporation ProductsDescription
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq]
Specifications
Specifications
| Accession Number | P42702 |
| For Use With (Application) | SDS-PAGE |
| Formulation | Lyophilized |
| Gene ID (Entrez) | 3977 |
| Molecular Weight (g/mol) | 125-135kDa |
| Name | LIFR (Human) Recombinant Protein |
| Preparation Method | Mammalian cell (HEK293) expression system |
| Purification Method | Ion exchange column and HPLC reverse phase column |
| Quantity | 20 μg |
| Storage Requirements | Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at 4°C for one month. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.