Invitrogen™ Human LILRA3 (CD85e, ILT6) His-tag Recombinant Protein

Catalog No.	Quantity
PIRP88079	100 μg
PIRP88080	1 mg

Catalog No. PIRP88079 Supplier Invitrogen™ Supplier No. RP88079

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (500 μL) be added to the vial to prepare a stock solution of 2 mg/mL. Concentration is measured by UV.

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).

Specifications

• Accession Number: Q8N6C8
• Concentration: 0.25 mg/mL
• For Use With (Application): Control, Neutralization
• Format: Lyophilized
• Formulation: PBS with 5% mannitol, 5% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
• Gene ID (Entrez): 11026
• Molecular Weight (g/mol): 57-66 kDa
• Name: Human LILRA3 (CD85e, ILT6) His-tag
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μg
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Endotoxin Concentration: <1.0 EU/μg
• Gene Alias: CD85 antigen-like family member E; CD85e; HM31; HM43; ILT6; ILT-6; Immunoglobulin-like transcript 6; leucocyte Ig-like receptor A3; leukocyte immunoglobulin like receptor A3; leukocyte immunoglobulin-like receptor 4; leukocyte immunoglobulin-like receptor A3; leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3; LILRA3; LIR4; LIR-4; Monocyte inhibitory receptor HM43/HM31
• Common Name: LILRA3
• Gene Symbol: LILRA3
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Human LILRA3, amino acids Met1-Glu439 (Accession # AAH28208.1) with a C-terminal His-tag
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: HEK293 cells
• Form: Lyophilized
• Purity or Quality Grade: >85% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.