Invitrogen™ Human LILRB5 (CD85c, LIR-8) Fc Chimera Recombinant Protein

Catalog No.	Quantity
PIRP88135	100 μg
PIRP88136	1 mg

Catalog No. PIRP88135 Supplier Invitrogen™ Supplier No. RP88135

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (1000 μL) be added to the vial to prepare a stock solution of 1 mg/mL. Concentration is measured by UV.

This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.

Specifications

• Accession Number: O75023
• Concentration: 1 mg/mL
• For Use With (Application): Control, Neutralization
• Format: Lyophilized
• Formulation: PBS with 5% mannitol, 5% trehalose and no preservative; pH 7.4
• Gene ID (Entrez): 10990
• Molecular Weight (g/mol): 91.35 kDa
• Name: Human LILRB5 (CD85c, LIR-8) Fc Chimera
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μg
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Endotoxin Concentration: <1.0 EU/μg
• Gene Alias: CD85 antigen-like family member C; CD85C; leucocyte Ig-like receptor B5; leukocyte immunoglobulin like receptor B5; leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5; LILRB5; LIR8; LIR-8
• Common Name: LILRB5
• Gene Symbol: LILRB5
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: Fc-tag
• Sequence: Human LILRB5, amino acids Met1-Gly458 (Accession # NP_006831.1) with a C-terminal human IgG1 Fc region
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: HEK293 cells
• Form: Lyophilized
• Purity or Quality Grade: >90% as determined by SDS-PAGE.