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Gibco™ Human MANF Recombinant Protein, PeproTech®
SDP

E. coli Recombinant Protein

Supplier:  Gibco™ 45006100UG

Encompass

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Catalog No. 45006100UG


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Description

Description

The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

P55145
protein with no preservative
18.1
100 μg
-20°C
<1 EU/μg
MANF
Unconjugated
LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL
≥ 98% by SDS-PAGE gel and HPLC analyses.
Functional Assay
7873
Human MANF
E. coli
RUO
3230402M22Rik; AA407711; AA408789; AA673178; Arginine-rich protein; arginine-rich, mutated in early stage tumors; ARMET; ARP; D17914; D18Mgi17; Manf; mesencephalic astrocyte derived neurotrophic factor; mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET
Human
Recombinant
Lyophilized
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